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Relationship between circulating serum osteoprotegerin and total receptor activator of nuclear κ-B ligand levels, triglycerides, and coronary calcification in postmenopausal women.

Identifieur interne : 001668 ( Main/Exploration ); précédent : 001667; suivant : 001669

Relationship between circulating serum osteoprotegerin and total receptor activator of nuclear κ-B ligand levels, triglycerides, and coronary calcification in postmenopausal women.

Auteurs : Indu G. Poornima [États-Unis] ; Rachel H. Mackey ; Alhaji M. Buhari ; Jane A. Cauley ; Karen A. Matthews ; Lewis H. Kuller

Source :

RBID : pubmed:24473535

Descripteurs français

English descriptors

Abstract

This study evaluates the relationship of blood osteoprotegerin (OPG) and receptor activator of nuclear κ-B ligand (RANKL) levels with coronary artery calcium (CAC) and cardiovascular risk factors in two studies of postmenopausal women. OPG, a marker of bone turnover, and its ligand, RANKL, may contribute to cardiovascular disease risk.

DOI: 10.1097/GME.0000000000000127
PubMed: 24473535


Affiliations:


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Le document en format XML

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<nlm:affiliation>From the 1Division of Cardiology, Allegheny General Hospital, Pittsburgh, PA; 2Drexel University College of Medicine, Philadelphia, PA; 3Department of Epidemiology, Graduate School of Public Health, and 4Department of Psychiatry, Epidemiology, and Psychology, University of Pittsburgh, Pittsburgh, PA.</nlm:affiliation>
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<wicri:cityArea>From the 1Division of Cardiology, Allegheny General Hospital, Pittsburgh, PA; 2Drexel University College of Medicine, Philadelphia, PA; 3Department of Epidemiology, Graduate School of Public Health, and 4Department of Psychiatry, Epidemiology, and Psychology, University of Pittsburgh, Pittsburgh</wicri:cityArea>
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<term>Calcinosis (physiopathology)</term>
<term>Coronary Artery Disease (blood)</term>
<term>Coronary Artery Disease (physiopathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Osteoprotegerin (blood)</term>
<term>Postmenopause (blood)</term>
<term>Predictive Value of Tests</term>
<term>RANK Ligand (blood)</term>
<term>Receptor Activator of Nuclear Factor-kappa B (blood)</term>
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<term>Humains</term>
<term>Ligand de RANK (sang)</term>
<term>Maladie des artères coronaires (physiopathologie)</term>
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<term>Post-ménopause (sang)</term>
<term>Récepteur activateur du facteur nucléaire Kappa B (sang)</term>
<term>Triglycéride (sang)</term>
<term>Valeur prédictive des tests</term>
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<term>Osteoprotegerin</term>
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<term>Receptor Activator of Nuclear Factor-kappa B</term>
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<term>Coronary Artery Disease</term>
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<term>Calcinose</term>
<term>Maladie des artères coronaires</term>
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<term>Calcinosis</term>
<term>Coronary Artery Disease</term>
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<term>Calcinose</term>
<term>Ligand de RANK</term>
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<term>Marqueurs biologiques</term>
<term>Ostéoprotégérine</term>
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<div type="abstract" xml:lang="en">This study evaluates the relationship of blood osteoprotegerin (OPG) and receptor activator of nuclear κ-B ligand (RANKL) levels with coronary artery calcium (CAC) and cardiovascular risk factors in two studies of postmenopausal women. OPG, a marker of bone turnover, and its ligand, RANKL, may contribute to cardiovascular disease risk.</div>
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